Browsing Department of Pharmaceutical Engineering by Author "Goel, Bharat"

Browsing Department of Pharmaceutical Engineering by Author "Goel, Bharat"

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  • Goel, Bharat; Dey, Biswajit; Chatterjee, Essha; Tripathi, Nancy; Bhardwaj, Nivedita; Kumar, Sanjay; Guru, Santosh Kumar; Jain, Shreyans K. (American Chemical Society, 2022-08)
    Gloriosine, a colchicine-like natural product, is widely obtained from Gloriosa superba roots. Despite having remarkable anticancer potential, colchicine could not pave its way to the clinic, while gloriosine is yet to be ...
  • Bhardwaj, Nivedita; Goel, Bharat; Tripathi, Nancy; Sahu, Bharat; Jain, Shreyans K. (Elsevier Masson s.r.l., 2022-04)
    Metastasis by and large is responsible for the worldwide deaths associated with various types of cancers. The metastatic variant of cancer cells generated due to the cellular heterogeneity and abnormal activation of various ...
  • Tripathi, Nancy; Goel, Bharat; Bhardwaj, Nivedita; Vishwakarma, Ram; Jain, Shreyans K. (American Chemical Society, 2022-08)
    The Spike (S) protein of SARS-CoV-2 expressed on the viral cell surface is of particular importance as it facilitates viral entry into the host cells. The S protein is heavily glycosylated with 22 N-glycosylation sites and ...
  • Goel, Bharat; Tripathi, Nancy; Bhardwaj, Nivedita; Kumar, Amit; Jain, Shreyans K. (Taylor and Francis Ltd., 2022-01)
    A fast and efficient method for synthesising ipomone (4), a bicyclo[3.2.1]octanone containing aromatised derivative, from gibberellic acid (1) has been developed using molecular iodine as a mild and effective mediator under ...
  • Goel, Bharat; Tripathi, Nancy; Bhardwaj, Nivedita; Jain, Shreyans K. (Taylor and Francis Ltd., 2022-04-16)
    A fast and efficient method for synthesising ipomone (4), a bicyclo[3.2.1]octanone containing aromatised derivative, from gibberellic acid (1) has been developed using molecular iodine as a mild and effective mediator under ...
  • Goel, Bharat; Reddy, Harichander; Cholkar, Anjali; Kumar, Sanjeev; Guru, Santosh Kumar; Jain, Shreyans K. (Taylor and Francis Ltd., 2022)
    A new colchinoid compound, identified as N-deacetyl-N-formylcornigerine (1), named glorigerine was isolated from the roots of Gloriosa superba, along with two known compounds. The structures of isolated compounds were ...
  • Goel, Bharat; Tiwari, Anoop Kumar; Pandey, Rajeev Kumar; Singh, Akhand Pratap; Kumar, Sujeet; Sinha, Abhishek; Jain, Shreyans K.; Khattri, Arun (Neoplasia Press, Inc., 2022-07)
    Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) being major risk factors. Despite advances in numerous ...

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