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Browsing Department of Pharmaceutical Engineering by Author "Dubey, Pawan K."

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Di-(2-ethylhexyl) phthalate (DEHP) inhibits steroidogenesis and induces mitochondria-ROS mediated apoptosis in rat ovarian granulosa cells

Tripathi, Anima; Pandey, Vivek; Sahu, Alakh N.; Singh, Alok; Dubey, Pawan K. (Royal Society of Chemistry, 2019-02-04)

Increased oxidative stress (OS) due to ubiquitous exposure to di-(2-ethylhexyl) phthalate (DEHP) can affect the quality of oocytes by inducing apoptosis and hampering granulosa cell mediated steroidogenesis. This study was ...
Quality by design–based development and optimization of fourth-generation ternary solid dispersion of standardized Piper longum extract for melanoma therapy

Mohapatra, Debadatta; Kumar, Dulla Naveen; Shreya, Singh; Pandey, Vivek; Dubey, Pawan K.; Agrawal, Ashish Kumar; Sahu, Alakh N (Springer, 2023-06-09)

The study aimed to enhance the solubility, dissolution, and oral bioavailability of standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary solid dispersion (SD) for melanoma therapy. With ...
Tinospora cordifolia Leaves Derived Carbon dots for Cancer Cell Bioimaging Free radical Scavenging, and Fe3+ Sensing Applications

Mohapatra, Debadatta; Pratap, Ravi; Pandey, Vivek; Dubey, Pawan K.; Agrawal, Ashish K.; Parmar, Avanish S.; Sahu, Alakh N. (Springer, 2022-01)

Herein, we report the fabrication of Tinospora cordifolia leaves-derived carbon dots(TCLCDs) from aqueous extract of leaves as carbon source via simple,environmentally friendly, hydrothermal carbonization (HTC) technique. ...

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