Iodine-mediated one-step synthesis of ipomone from gibberellic acid

dc.contributor.author	Goel, Bharat
dc.contributor.author	Tripathi, Nancy
dc.contributor.author	Bhardwaj, Nivedita
dc.contributor.author	Kumar, Amit
dc.contributor.author	Jain, Shreyans K.
dc.date.accessioned	2023-04-26T05:11:52Z
dc.date.available	2023-04-26T05:11:52Z
dc.date.issued	2022-01
dc.identifier.issn	14786419
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/2284
dc.description	This paper is submitted by the author of IIT (BHU), Varanasi	en_US
dc.description.abstract	A fast and efficient method for synthesising ipomone (4), a bicyclo[3.2.1]octanone containing aromatised derivative, from gibberellic acid (1) has been developed using molecular iodine as a mild and effective mediator under heating conditions in a single step. Evidence was obtained that the reaction simultaneously proceeds through aromatisation and pinacol-pinacolone type 1,2-alkyl shift. Use of excess iodine afforded iodomethyl derivative (5) that could serve as starting material for the synthesis of additional analogs.	en_US
dc.language.iso	en	en_US
dc.publisher	Taylor and Francis Ltd.	en_US
dc.relation.ispartofseries	Natural Product Research;
dc.subject	1,2-alkyl shift	en_US
dc.subject	gibberellic acid	en_US
dc.subject	iodination	en_US
dc.subject	ipomone	en_US
dc.subject	natural product	en_US
dc.title	Iodine-mediated one-step synthesis of ipomone from gibberellic acid	en_US
dc.type	Article	en_US