Abstract:
Chitosan-based hydrogel has been reported for biomedical applications in the area of
tissue engineering, wound healing, and drug delivery. However, the use of chitosan
involves the dissolution of chitosan in various types of acidic solvents (hydrochloric acid,
acetic acid), which may impart toxicity to the hydrogel. Generally, these acids are
very toxic in nature. If any residual amount of acid is present in the final product, it may
leach out to the nearby tissues and may cause damage to the tissue. The current thesis
deals with the development of chitosan-based hydrogels, which excludes the use of
acidic solvents. Full abstract is available in the attachment.