Force induced melting of the constrained DNA

dc.contributor.author	Singh, A.R.
dc.contributor.author	Giri, D.
dc.contributor.author	Kumar, S.
dc.date.accessioned	2021-10-14T05:45:13Z
dc.date.available	2021-10-14T05:45:13Z
dc.date.issued	2010-06-21
dc.identifier.issn	00219606
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1800
dc.description.abstract	We develop a simple model to study the effects of the applied force on the melting of a double stranded DNA (dsDNA). Using this model, we could study the stretching, unzipping, rupture and slippagelike transition in a dsDNA. We show that in absence of an applied force, the melting temperature and the melting profile of dsDNA strongly depend on the constrained imposed on the ends of dsDNA. The nature of the phase boundary of the force-temperature diagram, which separates the zipped and the open state for the shearinglike transition is remarkably different than the DNA unzipping.	en_US
dc.description.sponsorship	Journal of Chemical Physics	en_US
dc.language.iso	en	en_US
dc.relation.ispartofseries	Issue 23;Volume 132
dc.subject	Double-stranded DNA (ds-DNA);	en_US
dc.subject	Force-induced melting;	en_US
dc.subject	biomechanics;	en_US
dc.subject	transition temperature;	en_US
dc.title	Force induced melting of the constrained DNA	en_US
dc.type	Article	en_US