Force induced unfolding of biopolymers in a cellular environment: A model study

dc.contributor.author	Singh, A.R.
dc.contributor.author	Giri, D.
dc.contributor.author	Kumar, S.
dc.date.accessioned	2021-10-07T06:59:45Z
dc.date.available	2021-10-07T06:59:45Z
dc.date.issued	2009
dc.identifier.issn	00219606
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1769
dc.description.abstract	Effect of molecular crowding and confinement experienced by protein in the cell during unfolding has been studied by modeling a linear polymer chain on a percolation cluster. It is known that internal structure of the cell changes in time, however, they do not change significantly from their initial structure. In order to model this we introduce the correlation among the different disorder realizations. It was shown that the force-extension behavior for correlated disorder in both constant force ensemble and constant distance ensemble is significantly different than the one obtained in absence of molecular crowding.	en_US
dc.description.sponsorship	Journal of Chemical Physics	en_US
dc.language.iso	en	en_US
dc.relation.ispartofseries	Issue 6;Volume 131
dc.subject	Biopolymers;	en_US
dc.subject	Correlated disorder;	en_US
dc.subject	Molecular crowding;	en_US
dc.subject	computer simulation;	en_US
dc.title	Force induced unfolding of biopolymers in a cellular environment: A model study	en_US
dc.type	Article	en_US