Browsing by Author "Waiker, Digambar Kumar"

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Design, Synthesis, and Biological Evaluation of Some Heterocyclic Multifunctional Molecular Hybrids for Alzheimer’s disease Therapy

Waiker, Digambar Kumar (IIT(BHU) Varanasi, 2023)

Abstract is available in the content.
Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer’s Disease

Waiker, Digambar Kumar; Verma, Akash; Saraf, Poorvi; Gajendra, T.A.; Krishnamurthy, Sairam; Chaurasia, Rameshwar Nath; Shrivastava, Sushant Kumar (American Chemical Society, 2023-03-02)

A series of some novel compounds (SD-1-17) were designed following a molecular hybridization approach, synthesized, and biologically tested for hAChE, hBChE, hBACE-1, and Aβ aggregation inhibition potential to improve ...
Synthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitors

Shrivastava, Sushant Kumar; Sinha, Ojaswi; Kumar, Munish; Waiker, Digambar Kumar; Verma, Akash; Tripathi, Prabhash Nath; Bhardwaj, Bhagwati; Saraf, Poorvi (Springer, 2022-09)

In our present work, some novel substituted 4-phenyl-5-vinylpyrrolidin-2-one derivatives were designed, synthesized, and evaluated for their γ-aminobutyric acid-aminotransferase (GABA-AT) inhibition and in-vivo anticonvulsant ...

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