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Browsing by Author "Padhi, Aditya K."

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Comprehensive analysis of liquid–liquid phase separation propensities of HSV-1 proteins and their interaction with host factors

Subedi, Sushma; Nag, Niharika; Shukla, Harish; Padhi, Aditya K.; Tripathi, Timir (John Wiley and Sons Inc, 2023-10-05)

In recent years, it has been shown that the liquid–liquid phase separation (LLPS) of virus proteins plays a crucial role in their life cycle. It promotes the formation of viral replication organelles, concentrating viral ...
Computational Protein Design for COVID-19 Research and Emerging Therapeutics

Kalita, Parismita; Tripathi, Timir; Padhi, Aditya K. (American Chemical Society, 2022)

As the world struggles with the ongoing COVID-19 pandemic, unprecedented obstacles have continuously been traversed as new SARS-CoV-2 variants continually emerge. Infectious disease outbreaks are unavoidable, but the ...
Delineating the Structure-Dynamics-Binding Differences among BA.1, BA.4/5, and BF.7 SARS-CoV-2 Variants through Atomistic Simulations: Correlation with Structural and Epidemiological Features

Joshi, Aryaman; Maurya, Shweata; Mahale, Atharva; Rath, Soumya Lipsa; Tripathi, Timir; Padhi, Aditya K. (American Chemical Society, 2023-10-03)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA virus possessing a spike (S) protein that facilitates the entry of the virus into human cells. The emergence of highly transmissible and fit SARS-CoV-2 ...
Geranyl Diphosphate Synthase (CrtE) Inhibition Using Alendronate Enhances Isoprene Production in Recombinant Synechococcus elongatus UTEX 2973: A Step towards Isoprene Biorefinery

Yadav, Indrajeet; Rautela, Akhil; Gangwar, Agendra; Kesari, Vigya; Padhi, Aditya K.; Kumar, Sanjay (MDPI, 2023-02-24)

A hemiterpene, isoprene, is commercially produced from crude oil refining processes. As a result of fossil fuel depletion, isoprene production process development is gaining attention from recombinant cyanobacteria and ...
Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function

Chang, Jingjie; Yamashita, Motoi; Padhi, Aditya K.; Zhang, Kam Y. J.; Taniuchi, Ichiro (Frontiers Media SA, 2023-08-17)

AIOLOS, encoded by IKZF3, is a member of the IKZF family of proteins that plays an important role in regulating late B-cell differentiation. Human individuals heterozygous for the AIOLOS p.N160S variant displayed impaired ...
Multi-pathogen based chimeric vaccine to fight against COVID-19 and concomitant coinfections

Ojha, Rupal; Singh, Satyendra; Gupta, Nidhi; Kumar, Ketan; Padhi, Aditya K.; Prajapati, Vijay Kumar (Springer Science and Business Media B.V., 2023-05-06)

Background: COVID-19 has proved to be a fatal disease of the year 2020, due to which thousands of people globally have lost their lives, and still, the infection cases are at a high rate. Experimental studies suggested ...

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Browsing by Author "Padhi, Aditya K."

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