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Browsing by Author "Kumar, Dulla Naveen"

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A Bacteriophage Microgel Effectively Treats the Multidrug-Resistant Acinetobacter baumannii Bacterial Infections in Burn Wounds

Dehari, Deepa; Chaudhuri, Aiswarya; Kumar, Dulla Naveen; Patil, Rohit; Gangwar, Mayank; Rastogi, Sonam; Kumar, Dinesh; Nath, Gopal; Agrawal, Ashish Kumar (Multidisciplinary Digital Publishing Institute (MDPI), 2023-06-29)

Multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) is one of the major pathogens present in burn wound infections. Biofilm formation makes it further challenging to treat with clinically available antibiotics. ...
Combination Therapy Comprising Paclitaxel and 5-Fluorouracil by Using Folic Acid Functionalized Bovine Milk Exosomes Improves the Therapeutic Efficacy against Breast Cancer

Kumar, Dulla Naveen; Chaudhuri, Aiswarya; Dehari, Deepa; Shekher, Anusmita; Gupta, Subash C.; Majumdar, Shreyasi; Krishnamurthy, Sairam; Singh, Sanjay; Kumar, Dinesh; Agrawal, Ashish Kumar (MDPI, 2022-08)

Paclitaxel (PAC) has been approved by FDA for clinical use (Taxol®), yet dose-dependent severe toxicity due to the adjuvant Cremophor EL® in combination with ethanol is a major drawback. The drawbacks of the current therapy ...
Emergence of Nanotechnology as a Powerful Cavalry against Triple-Negative Breast Cancer (TNBC)

Chaudhuri, Aiswarya; Kumar, Dulla Naveen; Dehari, Deepa; Singh, Sanjay; Kumar, Pradeep; Bolla, Pradeep Kumar; Kumar, Dinesh; Agrawal, Ashish Kumar (MDPI, 2022-05)

Triplenegative breast cancer (TNBC) is considered one of the unmanageable types of breast cancer, involving devoid of estrogen, progesterone, and human epidermal growth factor receptor 2 (HER 2) receptors. Due to their ...
Exosomes as Emerging Drug Delivery and Diagnostic Modality for Breast Cancer: Recent Advances in Isolation and Application

Kumar, Dulla Naveen; Chaudhuri, Aiswarya; Aqil, Farrukh; Dehari, Deepa; Munagala, Radha; Singh, Sanjay; Gupta, Ramesh C.; Agrawal, Ashish Kumar (MDPI, 2022-03)

Breast cancer (BC) is the most common type of malignancy which covers almost one-fourth of all the cancers diagnosed in women. Conventionally, chemo-, hormonal-, immune-, sur-gery, and radiotherapy are the clinically ...
Lipid-Based Nanoparticles as a Pivotal Delivery Approach in Triple Negative Breast Cancer (TNBC) Therapy

Chaudhuri, Aiswarya; Kumar, Dulla Naveen; Shaik, Rasheed A.; Eid, Basma G.; Abdel-Naim, Ashraf B.; Md, Shadab; Ahmad, Aftab; Agrawal, Ashish Kumar (MDPI, 2022-09)

Triple-negative breast cancer is considered the most aggressive type of breast cancer among women and the lack of expressed receptors has made treatment options substantially limited. Recently, various types of nanoparticles ...
Quality by design–based development and optimization of fourth-generation ternary solid dispersion of standardized Piper longum extract for melanoma therapy

Mohapatra, Debadatta; Kumar, Dulla Naveen; Shreya, Singh; Pandey, Vivek; Dubey, Pawan K.; Agrawal, Ashish Kumar; Sahu, Alakh N (Springer, 2023-06-09)

The study aimed to enhance the solubility, dissolution, and oral bioavailability of standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary solid dispersion (SD) for melanoma therapy. With ...

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